Search results for "cancer immune tolerance"

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Extracellular Vesicles and Tumor-Immune Escape: Biological Functions and Clinical Perspectives

2020

The modulation of the immune system is one of the hallmarks of cancer. It is now widely described that cancer cells are able to evade the immune response and thus establish immune tolerance. The exploration of the mechanisms underlying this ability of cancer cells has always attracted the scientific community and is the basis for the development of new promising cancer therapies. Recent evidence has highlighted how extracellular vesicles (EVs) represent a mechanism by which cancer cells promote immune escape by inducing phenotypic changes on different immune cell populations. In this review, we will discuss the recent findings on the role of tumor-derived extracellular vesicles (TEVs) in re…

animal diseasesCellProgrammed Cell Death 1 Receptorchemical and pharmacologic phenomenapd-1/pd-l1 axisReviewBiologyCatalysisImmune toleranceInorganic Chemistrylcsh:ChemistryExtracellular VesiclesImmune systemNeoplasmsmedicineImmune ToleranceAnimalsHumansPhysical and Theoretical ChemistryMolecular Biologylcsh:QH301-705.5SpectroscopyMechanism (biology)Organic ChemistryCancerGeneral Medicinebiochemical phenomena metabolism and nutritionimmune checkpointsmedicine.diseasePhenotypeComputer Science ApplicationsCell biologyextracellular vesicles (evs) cancer immune toleranceThe Hallmarks of Cancermedicine.anatomical_structurelcsh:Biology (General)lcsh:QD1-999Cancer cellbacteriaTumor EscapeImmune checkpointImmunotherapyextracellular vesicles (EVs)cancer immune toleranceInternational Journal of Molecular Sciences

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PEPhysical Sciences and Engineering
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